Author

Xian Jin

Ewha Womans UniversityORCID 0000-0002-8273-0108Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Dong-Kyo LeeiD· 2 shared Hyun‐Ju KimiD· 2 shared Je‐Yong ChoiiD· 2 shared Sihoon LeeiD· 2 shared Xiangguo CheiD· 2 shared Doo Ri Park· 1 shared Hunsang LeeiD· 1 shared Keun HuriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenomics

Dong-Kyo LeeORCID

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2 papers

Recent·Most cited

Dimeric R25CPTH(1-34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice

Minsoo Noh, Xiangguo Che, Xian Jin, Dong-Kyo Lee, Hyun‐Ju Kim, Doo Ri Park, Soo Young Lee, Hunsang Lee, Thomas James Gardella, Je‐Yong Choi, Sihoon Lee

This study shows that the dimeric PTH variant R25CPTH(1-34) activates the PTH1R and improves bone formation in osteoporotic mice.

eLife · Mar 28, 2025Peer-reviewedGenomics

Phospholipase C β4 promotes RANKL-dependent osteoclastogenesis by interacting with MKK3 and p38 MAPK

Dong-Kyo Lee, Xian Jin, Poo-Reum Choi, Ying Jun Cui, Xiangguo Che, Sihoon Lee, Keun Hur, Hyun‐Ju Kim, Je‐Yong Choi

This study identifies PLCβ4 as a key regulator of RANKL-induced osteoclastogenesis by interacting with MKK3 and p38 MAPK, showing its potential as a therapeutic target for bone diseases.

Experimental & Molecular Medicine · Feb 2, 2025Peer-reviewedCell Biology