Vahap Canbay

This study identifies RHBDL2 as a calcium-activated rhomboid protease that suppresses EGFR signaling in keratinocytes by shedding its ectodomain, thereby limiting cell migration and invasion.

InstaNovo-P improves phosphorylated peptide detection and site localization in phosphoproteomics by using a transformer-based model fine-tuned on phosphoproteomics data.

This study shows that increased meprin α expression in mice leads to a psoriasis-like skin phenotype through degradation of dermokine, promoting hyperproliferation and inflammation.

The paper investigates dermokine's role in keratinocyte adhesion through multi-omics analysis, showing that dermokine loss increases p120 phosphorylation and reduces cell-cell adhesion.