Weihua Tian

This study identifies BNIP3L/NIX-mediated mitophagy as a critical pathway that limits Alzheimer's disease pathology and preserves neuronal function by maintaining mitochondrial health and reducing proteotoxicity.

This study investigates how O-mannose glycosylations on E-cadherin affect its protein interactions, showing O-Man-dependent changes in CDH1 associations with CDH3 and other proteins.

This study shows that removing glycosaminoglycans from extracellular vesicles increases their uptake and cargo delivery to target cells, suggesting glycan structures can be tuned for better drug delivery.

The paper investigates dermokine's role in keratinocyte adhesion through multi-omics analysis, showing that dermokine loss increases p120 phosphorylation and reduces cell-cell adhesion.

The paper maps O-Man glycoproteins in human cells and identifies substrate specificities of O-Man glycosylation pathways.