Dipankar Nandi

Comparative analysis of immunomodulatory effects of Artemisinin and Parthenolide on activation of immune cells and their roles in Salmonella Typhimurium infection

This study compares the immunomodulatory effects of Artemisinin and Parthenolide in vitro and in vivo, finding Parthenolide more effective in suppressing inflammation and immunopathology during Salmonella Typhimurium infection.

TCR-dependent and TCR-independent in-vitro T cell activation generate distinct functional, metabolic, and cytokine programs: Protein kinase C signalling augments anti-CD3+anti-CD28 responses

This study compares TCR-dependent and TCR-independent T cell activation methods, finding distinct functional, metabolic, and cytokine profiles, with PKC signaling enhancing CD3+CD28 responses.

Coregulation by arcA and fnr protects Salmonella Typhimurium from bile stress by maintaining redox homeostasis and membrane integrity

This study shows that arcA and fnr in Salmonella Typhimurium protect against bile stress by reducing ROS and maintaining membrane integrity through nitrate metabolism.

Identification of small-molecule adjuvants that enhance the sensitivity of Escherichia coli to nitrofurantoin: Roles of Lon and MarA

This study identifies small-molecule adjuvants, specifically salicylates, that enhance nitrofurantoin's efficacy against Escherichia coli by modulating Lon protease and MarA pathways.

Identification of 4-Amino-2-Nitrophenol as a novel inducer of phenotypic antibiotic resistance in Escherichia coli: roles of Lon protease and its substrate MarA

This study identifies 4-Amino-2-Nitrophenol as a novel inducer of phenotypic antibiotic resistance in E. coli, mediated by Lon protease and its substrate MarA through nitroreductase activity.

Global transcriptome analysis identifies nicotinamide metabolism to play key roles in IFN-gamma and nitric oxide modulated responses

This study identifies nicotinamide metabolism as a key modulator of IFN-gamma and nitric oxide responses through transcriptomic and metabolic analysis in macrophages.

High intracellular calcium amounts inhibit activation-induced proliferation of mouse T cells

This study shows high intracellular calcium inhibits T cell proliferation in vitro and reduces colitis in vivo, suggesting calcium modulation could treat autoimmune diseases.