Rafael Linden

This study shows that overexpressing Pou4f2 in late retinal progenitors generates RGC-like neurons with axonal projections to brain regions.

This paper shows that overexpressing Klf4 in retinal progenitor cells can reprogram them to generate retinal ganglion cells in vivo, with iRGCs surviving for up to 30 days.

This study shows that Neurogenin2 can reprogram Muller glia into retinal ganglion cell-like neurons, with efficiency comparable to ASCL1 but with distinct gene expression outcomes.