Author

Arielle L. Klepper

University of California, San FranciscoORCID 0000-0002-5227-5044Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:metagenomics· 1

Frequent Co-Authors

Bryan Castillo-RojasiD· 2 shared Joseph L. DeRisiiD· 2 shared Kelsey C. ZorniD· 2 shared Aaron BodanskyiD· 1 shared Andrew R. LaiiD· 1 shared Caroline B. Vissers· 1 shared Charlotte HurabielleiD· 1 shared Chun YeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Bryan Castillo-RojasORCID

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2 papers

Recent·Most cited

Longitudinal linear-epitope profiling of SLE identifies novel antigens associated with disease and disease activity

Charlotte Hurabielle, Yutong V Wang, Bryan Castillo-Rojas, Chung-Yu Wang, Colette M. Caspar, James Asaki, Monica T. Dayao, Max Calcoen, Eric Dean Merrill, Aaron Bodansky, Arielle L. Klepper, Elizabeth N Chung, Caroline B. Vissers, Kelsey C. Zorn, Mark Stuart Anderson, , Joseph L. DeRisi

This study identifies novel SLE autoantigens and links EBV-driven immunity to autoimmunity through longitudinal PhIP-seq and machine learning analysis.

bioRxiv · Oct 4, 2026 · PreprintImmunology

Humoral Immune Dysregulation Defines High-Risk Cirrhotic Ascites

Arielle L. Klepper, Matt S. Zinter, Tamara I. A. Roach, Sukhman Sidhu, Zoe Berman, Ishaan Dureja, Ravi Dandekar, Sammer Ganem, Karina Perlaza, Bryan Castillo-Rojas, Kelsey C. Zorn, Jacquelyn J. Maher, Jody L. Baron, Matthew Yocum, Andrew R. Lai, , Joseph L. DeRisi

The paper analyzes human ascites fluid to identify immune dysregulation features associated with poor outcomes in cirrhosis, finding that B cell dysfunction, not microbial translocation, defines high-risk cases.

bioRxiv · Oct 1, 2026 · PreprintImmunology