This study identifies novel SLE autoantigens and links EBV-driven immunity to autoimmunity through longitudinal PhIP-seq and machine learning analysis.

bioRxiv · Oct 4, 2026 · PreprintImmunology

Lung adventitial fibroblasts support type 2 Tregs to shape the response to influenza infection

Anthony Chang, Joanna Balcerek, Sofia E. Caryotakis, Kennedi B. Pyper, Peri R. Matatia, Elina B. Wells, Tatsuya Tsukui, Nathan A. Ewing-Crystal, Eric Dean Merrill, Nicholas M. Mroz, Madelene W. Dahlgren, Kelly M. Cautivo, Marcela T Taruselli, Hiromi Nakao-Inoue, Anna Victoria Molofsky, , Ari B. Molofsky

The paper identifies IAV-driven fibroblast states and shows that loss of TGFβ signaling enhances immuno-modulatory fibroblasts, supporting T2-Tregs to improve lung outcomes.

bioRxiv · Apr 9, 2026 · PreprintImmunology

Dynamic fibroblast-immune interactions shape wound healing after brain injury

Nathan A. Ewing-Crystal, Nicholas M. Mroz, Amara Larpthaveesarp, Carlos O. Lizama, Remy Pennington, Pailin Chiaranunt, Jason I. Dennis, Anthony A. Chang, Eric Dean Merrill, Sofia E. Caryotakis, Nikhita Kirthivasan, Leon Teo, Tatsuya Tsukui, Aditya Katewa, Gabriel L. McKinsey, , Ari B. Molofsky

This study identifies dynamic fibroblast-immune interactions that regulate CNS wound healing and neuroinflammation after brain injury.

Nature · Sep 3, 2025Peer-reviewedImmunology

The emerging fungal pathogen Candida auris induces IFNγ to colonize mammalian hair follicles

Eric Dean Merrill, Victoria Prudent, Parna Moghadam, Abram Rodriguez, Charlotte Hurabielle, Elina Wells, Pauline Basso, Tiffany C. Scharschmidt, Michael D. Rosenblum, Ari B. Molofsky, Suzanne M. Noble

This study compares the skin colonization of Candida auris and C. albicans, finding that C. auris induces IFNγ to enhance its colonization of hair follicles by impairing keratinocyte function.

bioRxiv · Jan 15, 2025 · PreprintImmunology