Yong Wook Kim

This paper introduces EYClamp, a de novo designed enzyme for photo-proximity labeling of E3 ligase neighborhoods in live cells, identifying over 1,500 candidate neighbors for four E3 ligases.

The paper compares subcutaneous and omental adipose tissue in humans, finding distinct transcriptional identities and remodeling strategies linked to metabolic risk.

The paper identifies age-dependent structural changes in the human plasma proteome using Covalent Protein Painting and MRM-LC-MS/MS, revealing patterns that may serve as structural biomarkers.

ProMiSE evaluates protein multi-state prediction models using a curated dataset of biological conformational changes, revealing limitations in capturing functionally relevant dynamics.

This study identifies how NbPtr1, an NLR receptor, recognizes multiple effectors through interactions with NOI-domain proteins, revealing a mechanism of decoy diversification in plant immunity.