Author

Oscar A. Negrón

Moderna Therapeutics (United States)ORCID 0000-0002-5234-8397Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Assay:spatial transcriptomics· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Eric M. PearlmaniD· 2 shared Michaela Ellen MarshalliD· 2 shared Mihaela G. GadjevaiD· 2 shared Nicole M. ChumbleriD· 2 shared Serena AbbondanteiD· 2 shared Ankush Tyagi· 1 shared Arne RietschiD· 1 shared Brandon Jones· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

Eric M. PearlmanORCID

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2 papers

Recent·Most cited

Spatial transcriptomics identifies the Pseudomonas aeruginosa major outer membrane protein OprF as a critical factor in blinding corneal infections

Serena Abbondante, Hao Zhu, Nicole M. Chumbler, Oscar A. Negrón, Michaela Ellen Marshall, Ankush Tyagi, Arne Rietsch, Eric M. Pearlman, Mihaela G. Gadjeva

The paper identifies OprF as critical for Pseudomonas aeruginosa virulence in corneal infections by linking it to ExoT expression and ROS inhibition.

bioRxiv · May 20, 2026 · PreprintMicrobiology

Spatial transcriptomics identifies novel Pseudomonas aeruginosa virulence factors

Hao Zhou, Oscar A. Negrón, Serena Abbondante, Michaela Ellen Marshall, Brandon Jones, Edison Ong, Nicole M. Chumbler, Christopher D. Tunkey, Groves Dixon, Haining Lin, Obadiah J. Plante, Eric M. Pearlman, Mihaela G. Gadjeva

This study uses spatial transcriptomics to identify novel Pseudomonas aeruginosa virulence factors and host-pathogen interactions in ocular infection.

Cell Genomics · Mar 1, 2025Peer-reviewedMicrobiology