Author

Mihaela G. Gadjeva

Moderna Therapeutics (United States)ORCID 0000-0002-9014-386XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Assay:spatial transcriptomics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Edison OngiD· 2 shared Eric M. PearlmaniD· 2 shared Hao ZhouiD· 2 shared Michaela Ellen MarshalliD· 2 shared Nicole M. ChumbleriD· 2 shared Oscar A. NegróniD· 2 shared Serena AbbondanteiD· 2 shared Allyson E. SheaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

Edison OngORCID

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Author profile →

4 papers

Recent·Most cited

Spatial transcriptomics identifies the Pseudomonas aeruginosa major outer membrane protein OprF as a critical factor in blinding corneal infections

Serena Abbondante, Hao Zhu, Nicole M. Chumbler, Oscar A. Negrón, Michaela Ellen Marshall, Ankush Tyagi, Arne Rietsch, Eric M. Pearlman, Mihaela G. Gadjeva

The paper identifies OprF as critical for Pseudomonas aeruginosa virulence in corneal infections by linking it to ExoT expression and ROS inhibition.

bioRxiv · May 20, 2026 · PreprintMicrobiology

Emerging Pathogens in Urinary Tract Infections: Virulence and Phenotypic Characterization of Pseudomonas aeruginosa strains

Rachel C. Fleck, Olena Gorodyna, Hao Zhou, Hannah Bryant, Mihaela G. Gadjeva, Allyson E. Shea

This study characterizes Pseudomonas aeruginosa as an emerging uropathogen in UTIs, identifying antibiotic resistance patterns, virulence factors, and associations with patient demographics and catheter use.

mSphere · May 13, 2026Peer-reviewedMicrobiology

Spatial transcriptomics identifies novel Pseudomonas aeruginosa virulence factors

Hao Zhou, Oscar A. Negrón, Serena Abbondante, Michaela Ellen Marshall, Brandon Jones, Edison Ong, Nicole M. Chumbler, Christopher D. Tunkey, Groves Dixon, Haining Lin, Obadiah J. Plante, Eric M. Pearlman, Mihaela G. Gadjeva

This study uses spatial transcriptomics to identify novel Pseudomonas aeruginosa virulence factors and host-pathogen interactions in ocular infection.

Cell Genomics · Mar 1, 2025Peer-reviewedMicrobiology

mtx-COBRA: Subcellular localization prediction for bacterial proteins

Isha Arora, Arkadij Kummer, Hao Zhou, Mihaela G. Gadjeva, Eric J. Ma, Gwo‐Yu Chuang, Edison Ong

mtx-COBRA improves subcellular localization prediction for bacterial proteins, outperforming PSORTb in accuracy for proteins with unknown localization.

Computers in Biology and Medicine · Feb 10, 2024Peer-reviewedBioinformatics