Author

Obadiah J. Plante

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:non-human primate· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Andrea Carfı́iD· 2 shared Cailin E. Deal· 2 shared Brandon Jones· 1 shared Christopher D. Tunkey· 1 shared Dawn M. DudleyiD· 1 shared Devin SokiD· 1 shared Edison OngiD· 1 shared Eric M. PearlmaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Andrea Carfı́ORCID

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Author profile →

3 papers

Recent·Most cited

Harnessing mRNA for the expression of monoclonal IgG and IgA in non-human primates.

Romy Rouzeau, Hayden R. Schmidt, Cailin E. Deal, Joel D. Allen, Dawn M. Dudley, Iszac Burton, Eva G. Rakasz, Obadiah J. Plante, Max Crispin, Andrea Carfı́, Devin Sok

This paper demonstrates the feasibility of expressing monoclonal IgG and IgA antibodies in non-human primates using mRNA-LNPs, showing both isotypes retain HIV-neutralizing function and native-like glycosylation.

Frontiers in Immunology · Jan 16, 2026Peer-reviewedImmunology

Maternal transfer of mRNA LNP-derived, pathogen-specific, monoclonal IgG to suckling mice

Jennifer E. Doering, Yetunde Adewunmi, Cailin E. Deal, Obadiah J. Plante, Andrea Carfı́, Nicholas John Mantis

This study demonstrates that mRNA-LNPs can deliver pathogen-specific monoclonal IgG into breast milk, enabling transfer of functional antibodies to suckling mice.

bioRxiv · Mar 12, 2025 · PreprintImmunology

Spatial transcriptomics identifies novel Pseudomonas aeruginosa virulence factors

Hao Zhou, Oscar A. Negrón, Serena Abbondante, Michaela Ellen Marshall, Brandon Jones, Edison Ong, Nicole M. Chumbler, Christopher D. Tunkey, Groves Dixon, Haining Lin, Obadiah J. Plante, Eric M. Pearlman, Mihaela G. Gadjeva

This study uses spatial transcriptomics to identify novel Pseudomonas aeruginosa virulence factors and host-pathogen interactions in ocular infection.

Cell Genomics · Mar 1, 2025Peer-reviewedMicrobiology