Author

François‐Xavier Mauvais

Centre National de la Recherche ScientifiqueORCID 0000-0002-5240-4280Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alberto Buson· 1 shared Alison D. Findlay· 1 shared Anastasia MpakaliiD· 1 shared Dieter W. HamprechtiD· 1 shared Efstratios StratikosiD· 1 shared Galateia GeorgakiiD· 1 shared Jonathan S. FootiD· 1 shared Peter Van EndertiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Alberto Buson

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1 paper

Recent·Most cited

BiochemistryProtein SciencePeer-reviewedAug 21, 2024

Stabilization of the open conformation of Insulin-Regulated Aminopeptidase by a novel substrate-selective small molecule inhibitor

Anastasia Mpakali, Galateia Georgaki, Alberto Buson…·Efstratios Stratikos

This paper identifies a nanomolar inhibitor of IRAP that stabilizes its open conformation, revealing a conformation-specific mechanism of action and insights into its catalytic cycle.

4 citations

experimental assaydrug response / drug discovery

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