Author

Svetlana Pasteuning-Vuhman

Utrecht UniversityORCID 0000-0002-5250-5620Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandro Moro· 1 shared Andreia Gomes‐DuarteiD· 1 shared Annabel Timmers· 1 shared Channa E. Jakobs· 1 shared Jamie K. WongiD· 1 shared Linda BorstiD· 1 shared Maarten A. F. AltelaariD· 1 shared Madhurima ChatterjeeiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alessandro Moro

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2 papers

Recent·Most cited

NeuroscienceMolecular Therapy AdvancesPeer-reviewedJul 29, 2026

AAV-Delivered Anti-PC-OxPL Antibody Fragments: A NovelTherapeutic Approach to Target ALS

Andreia Gomes‐Duarte, Jamie K. Wong, Alessandro Moro…·Sander J. H. van Deventer

This paper develops an AAV-delivered scFv antibody targeting PC-OxPL to reduce neurotoxicity and motor neuron death in ALS models.

DOI 10.1016/j.omta.2026.201822

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 5, 2022

Proteomic signature and mesenchymal stromal/stem cell-derived extracellular vesicle treatment of iPSC motor neurons from different ALS patient groups

Suzy Varderidou‐Minasian, Channa E. Jakobs, Svetlana Pasteuning-Vuhman…·R. Jeroen Pasterkamp

This study identifies proteomic signatures in iPSC-derived motor neurons with ALS mutations and shows MSC-EVs can reverse proteomic changes and restore neurite growth in FUS-ALS MNs.

2 citations

humanproteomics

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