Author

Marcus Hoffmann

Max Planck Institute for Dynamics of Complex Technical SystemsORCID 0000-0002-5259-255XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:zebrafish· 1

Frequent Co-Authors

Erdmann RappiD· 3 shared Frania J. Zuniga-BanuelosiD· 2 shared Udo ReichliD· 2 shared Christian ThieliD· 1 shared Clara BeckeriD· 1 shared Greta Lemke· 1 shared Joachim WittbrodtiD· 1 shared Kaisa PakariiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Erdmann RappORCID

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3 papers

Recent·Most cited

Immunoglobulin A Carries Sulfated N-glycans Primarily at the Tailpiece Site -- An Oxonium-Ion-Guided Approach for Site-Specific N-glycan Identification

Frania J. Zuniga-Banuelos, Greta Lemke, Marcus Hoffmann, Udo Reichl, Erdmann Rapp

This study identifies sulfated and O-acetylated N-glycans at specific sites in human IgA using a targeted N-glycoproteomic approach, revealing their potential as biomarkers and therapeutic targets.

bioRxiv · Jun 6, 2024 · PreprintMolecular Biology

New avenues for human blood plasma biomarker discovery via improved in-depth analysis of the low-abundant N-glycoproteome

Frania J. Zuniga-Banuelos, Marcus Hoffmann, Udo Reichl, Erdmann Rapp

The paper develops an improved N-glycoproteomic workflow to analyze low-abundant glycoproteins in human blood plasma, enabling the identification of 1,929 N-glycopeptides and 942 N-glycosites.

bioRxiv · Oct 22, 2023 · PreprintMolecular Biology

The medaka alg2 mutant is a model for hypo-N-glycosylation-associated retinitis pigmentosa

Sevinç Gücüm, Roman Sakson, Marcus Hoffmann, Valerian Grote, Clara Becker, Kaisa Pakari, Lars Beedgen, Christian Thiel, Erdmann Rapp, Thomas Ruppert, Thomas Thumberger, Joachim Wittbrodt

The paper models a hypo-N-glycosylation disorder in medaka fish, showing reduced N-glycan abundance and retinal degeneration, with mRNA rescue restoring viability.

Development · Jun 1, 2021Peer-reviewedDevelopmental Biology