Author

Xuyu Zhou

Chinese Academy of SciencesORCID 0000-0002-5259-7393Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Baidong HouiD· 1 shared Chang GuoiD· 1 shared Fangqing ZhaoiD· 1 shared Fuping ZhangiD· 1 shared Jie Fang GuoiD· 1 shared Li LiiD· 1 shared Qiuzhu Jin· 1 shared Ruiqiao He· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Baidong HouORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

TCR signal strength determines Treg instability and discrimination of self versus non-self antigens

Li Li, Jie Fang Guo, Ruiqiao He, Xin Chai, Chang Guo, Wei Xu, Xue Li Cao, Qiuzhu Jin, Fuping Zhang, Baidong Hou, Fangqing Zhao, Xuyu Zhou

The paper shows that strong TCR signals from foreign antigens destabilize Tregs, converting them into effector-like cells, while self-antigens preserve stability, revealing a mechanism for balancing immunity and tolerance.

bioRxiv · Feb 14, 2026 · PreprintImmunology