Author

Akane Yoshikawa

Tokyo Metropolitan Institute of Medical ScienceORCID 0000-0002-5271-5927Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Chihiro KakiuchiiD· 1 shared Daisuke KoshiyamaiD· 1 shared Fumichika Nishimura· 1 shared Fumio YamashitaiD· 1 shared Geneviève KonopkaiD· 1 shared Hidenori YamasueiD· 1 shared Hiroko SugawaraiD· 1 shared Jun IshigookaiD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Chihiro KakiuchiORCID

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2 papers

Recent·Most cited

Impairment of methylglyoxal detoxification systems causes mitochondrial dysfunction and schizophrenia-like behavioral deficits

Kazuya Toriumi, Stefano Berto, Shin Koike, Noriyoshi Usui, Takashi Dan, Kazuhiro Suzuki, Mitsuhiro Miyashita, Yasue Horiuchi, Akane Yoshikawa, Yuki Sugaya, Takaki Watanabe, Mai Asakura, Masanobu Kano, Yuki Ogasawara, Toshio Miyata, , Makoto Arai

This study shows that impaired methylglyoxal detoxification in mice leads to mitochondrial dysfunction and schizophrenia-like behaviors.

bioRxiv · Jul 8, 2020 · PreprintNeuroscience

Promoter activity-based case-control association study on SLC6A4 highlighting hypermethylation and altered amygdala volume in male patients with schizophrenia

Tempei Ikegame, Miki Bundo, Naohiro Okada, Y. Murata, Shinsuke Koike, Hiroko Sugawara, Takeo Saito, Masashi Ikeda, Keiho Owada, Masaki Fukunaga, Fumio Yamashita, Daisuke Koshiyama, Tatsunobu Natsubori, Norichika Iwashiro, Tatsuro Asai, , Kazuya Iwamoto

The paper identifies hypermethylation of SLC6A4 in male schizophrenia patients and links it to reduced amygdala volume and 5-HTTLPR genotype.

Schizophrenia Bulletin · May 27, 2020Peer-reviewedGenetics