Author

Stefán Sigurðsson

University of IcelandORCID 0000-0002-5284-0058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Kritika KirtyiD· 2 shared Maria Rose BustosiD· 2 shared Snævar SigurðssoniD· 2 shared Þorkell GuðjόnssoniD· 2 shared Adrián López García de LomanaiD· 1 shared Anna MinelloiD· 1 shared Anne Vincent‐SalomoniD· 1 shared Antonio GalarretaiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMolecular Biology

Kritika KirtyORCID

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3 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedDec 10, 2025

A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription

Anna Minello, Jesús Gómez-Escudero, Sree Rama Chaitanya Sridhara…·Aura Carreira

The paper investigates a BRCA2 truncating variant's effect on NF-κB-driven transcription by showing it disrupts the BRCA2-PCAF complex, reducing histone acetylation and impairing cell migration.

2 citations

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJun 9, 2025

MITF maintains genome stability in non-melanocytic cell lineages and suppresses Hippo pathway signaling

Drífa Hrund Guðmundsdóttir, Adrián López García de Lomana, Thejus B. Venkatesh…·Stefán Sigurðsson

This study shows MITF maintains genome stability in non-melanocytic cells by suppressing Hippo pathway signaling through LATS2 and ATR.

DOI 10.1101/2025.06.09.658599

humanexperimental assay

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GenomicsbioRxivPreprintOct 22, 2020

MITF Isoforms- Insights from an RNA-Seq study

Kritika Kirty, Snævar Sigurðsson, Þorkell Guðjόnsson…·Stefán Sigurðsson

The paper was withdrawn due to lack of co-author consent and is not to be cited as a reference.

DOI 10.1101/2020.10.22.351031

𝕏 PostBluesky