Natasha L. Tilston‐Lunel

Repurposing antiviral drugs as a new avenue for Klebsiella pneumoniae decolonization

This study identifies antiviral drugs with anti-Klebsiella pneumoniae activity, showing strain-specific effects and resistance mechanisms, suggesting their potential for gut decolonization.

Reverse genetics and comparative pathogenesis of Lone star virus.

This study generates recombinant Lone star virus (LSV) and compares its pathogenesis with related bandaviruses in mice, revealing differences in disease severity and immune response.

A novel antiviral strategy targeting human metapneumovirus through pH modulation in human airway epithelial cells

This study shows that PHOH-001, an inhaled alkaline buffer, reduces hMPV infection in airway epithelial cells by modulating pH and inhibiting viral replication and spread.

From prototype to outbreak: conserved pathogenesis of Oropouche virus in a novel murine pregnancy model highlights its public health implications

This study establishes a murine model showing Oropouche virus can vertically transmit from mother to fetus, confirming its long-standing ability and public health risks.

Type-2 diabetes mellitus enhances Klebsiella pneumoniae pathogenesis

This study shows that type 2 diabetes mellitus enhances Klebsiella pneumoniae pathogenesis by increasing gut colonization and lung infection severity.