J. Alexander Heimel

This study investigates whether short-term depression at thalamocortical synapses contributes to divisive normalization in mouse V1, finding no effect on contrast response or cross-orientation suppression.

LatenZy and latenZy2 are non-parametric, binning-free methods for estimating neural latency and detecting condition divergence in spiking data, outperforming standard approaches in precision and robustness.

The paper identifies modifier pathways for inborn errors of metabolism using multiomic data and gene regulatory networks from healthy populations.

The paper shows that mouse primary visual cortex exhibits spatiotemporal resonance patterns similar to humans, with multiple frequency peaks and standing wave characteristics in response to flicker.

The paper shows that subsecond neural fluctuations can generate noise invariance and inter-areal gating through population-level spiking dynamics.

This study shows that the superior colliculus in mice is causally involved in figure detection based on contrast, orientation, and phase, with stronger neural responses to figure elements than background elements.

The paper introduces a new family of statistical tests, ZETA-tests, designed to analyze neuronal spiking and autocorrelated time-series data with improved sensitivity and reduced false positives compared to traditional methods.

This study shows that thalamic plasticity, not just cortical plasticity, drives ocular dominance plasticity in adult visual cortex, highlighting the thalamus's role in learning.

The paper introduces a tool for aligning electrode tracks with histology and electrophysiological data across species, improving brain area assignment for neurons.

The paper shows mice habituate to repeated overhead visual stimuli but generalize freezing to novel shapes, indicating experience-dependent modulation of innate defensive responses.

ZETA is a parameter-free statistical test for neuronal responsiveness that includes more cells with fewer false positives compared to existing methods.

This study shows that delayed V1 neuronal responses are necessary for figure-ground segregation in mice, with VIP interneurons playing a key role through disinhibitory circuits.