Author

Aaron S. Bender

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Carmen ArgmanniD· 2 shared Sander M. HouteniD· 2 shared Adrian M. WongiD· 1 shared Alexander H. BedardiD· 1 shared Ambre M. Bertholet· 1 shared Bassem M. Shoucri· 1 shared Benjamin F. CravattiD· 1 shared Bruno N. MelilloiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenetics

Carmen ArgmannORCID

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2 papers

Recent·Most cited

A multiomic network approach uncovers disease modifying mechanisms of inborn errors of metabolism

Aaron S. Bender, Pablo Ranea‐Robles, Evan G. Williams, Mina Mirzaian, J. Alexander Heimel, Christiaan Nicolaas Levelt, Ronald J. A. Wanders, Johannes M. F. G. Aerts, Jun Zhu, Johan H. Auwerx, Sander M. Houten, Carmen Argmann

The paper identifies modifier pathways for inborn errors of metabolism using multiomic data and gene regulatory networks from healthy populations.

Journal of Inherited Metabolic Disease · May 30, 2025Peer-reviewedGenetics

A cold-inducible phospholipid--protein interaction in brown fat mitochondria optimizes thermogenic capacity

Yuta Shimanaka, Marc J. P. M. Tol, Christian Rocha-Roa, Matthew J. Jellinek, Liujuan Cui, Aaron S. Bender, Alexander H. Bedard, Madeleine G. Milner, Bruno N. Melillo, Bassem M. Shoucri, Adrian M. Wong, Kevin J. Williams, Linsey Stiles, Michael Shum, Thomas A. Weston, , Peter Tontonoz

The paper identifies LPCAT3 as a cold-regulated enzyme that generates AA-PE in BAT mitochondria, enhancing ETC efficiency and thermogenesis.

bioRxiv · May 15, 2025 · PreprintPhysiology