Author

Talia Baddour

University of California San DiegoORCID 0000-0002-5317-8203Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Brian A. AguadoiD· 3 shared Rayyan M. GorashiiD· 3 shared Arthur P. ArnoldiD· 1 shared Ashley K. NguyeniD· 1 shared Brisa PeñaiD· 1 shared Kati RichteriD· 1 shared Kevin R. KingiD· 1 shared Kristi S. AnsethiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBioengineering

Brian A. AguadoORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 16, 2026

Sex chromosome and gonadal regulation of cardiac myofibroblast activation decoupled using mechanically tunable hydrogels and the Four Core Genotypes model

Rayyan M. Gorashi, Talia Baddour, Kati Richter…·Lonnie D. Shea

This study decouples the effects of sex chromosomes and gonadal sex on cardiac myofibroblast activation using FCG mice and hydrogel cultures, revealing sex-specific gene and protein expression patterns.

DOI 10.64898/2026.10.13.758988

mousescRNA-seq

𝕏 PostBluesky

GenomicsArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedMay 28, 2026

Spatial transcriptomic profiling of the human aortic valve reveals cellular sex differences near sites of calcification

Talia Baddour, Van Kim Ninh, Rayyan M. Gorashi…·Brian A. Aguado

This study uses spatial transcriptomics to identify sex differences in gene expression and cell interactions near calcification sites in human aortic valves.

8 citationstop 1%

humanspatial transcriptomics

𝕏 PostBluesky

BioengineeringScience AdvancesPeer-reviewedMar 12, 2025

Y chromosome linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues

Rayyan M. Gorashi, Talia Baddour, Sarah J. Chittle…·Brian A. Aguado

The paper investigates how UTY modulates sex-specific methylation in male valvular fibroblasts in response to nanoscale extracellular matrix cues, promoting osteoblast-like cell phenotypes in aortic valve stenosis.

19 citationstop 1%

humanDNA methylation

𝕏 PostBluesky