Rayyan M. Gorashi

This study shows gonadal and chromosomal sex independently and together affect immune responses to implanted scaffolds in mice.

This study decouples the effects of sex chromosomes and gonadal sex on cardiac myofibroblast activation using FCG mice and hydrogel cultures, revealing sex-specific gene and protein expression patterns.

The paper identifies IGFBP2 as a sex-specific serum biomarker predicting Evogliptin resistance in female aortic valve stenosis patients.

This study shows TGF-β1 causes sex-specific cardiac myofibroblast activation and secreted factor differences on hydrogels, influencing fibrosis.

This study uses spatial transcriptomics to identify sex differences in gene expression and cell interactions near calcification sites in human aortic valves.

The paper investigates how UTY modulates sex-specific methylation in male valvular fibroblasts in response to nanoscale extracellular matrix cues, promoting osteoblast-like cell phenotypes in aortic valve stenosis.