Author
Meitian Wang
Paul Scherrer InstituteORCID 0000-0002-5340-3036Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 18 mutual co-author links4 papers
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Time-resolved functional rotation crystallography probes protein dynamics during enzymatic catalysis
Julien Martel, Nicolas Caramello, Sandrine Coquille, Eric Mathieu, Lucas Petit, P. Jacquet, Alexandre Appolaire, Filip Leonarski, Vincent Oliéric, Meitian Wang, Dominique Madern, Antoine Royant, Sylvain Engilberge
This paper introduces TR-FRX, a method to study protein dynamics during enzymatic catalysis using time-resolved crystallography, and applies it to lysozyme and malate dehydrogenase.
bioRxiv · Oct 3, 2026 · PreprintBiochemistry
Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography
Maximilian Wranik, Tobias Weinert, Chavdar Slavov, Tiziana Masini, Antonia Furrer, Natacha Gaillard, Dario Gioia, Marco Jacopo Ferrarotti, Daniel James, Hannah Glover, Melissa Carrillo, Demet Kekilli, Robin Stipp, Petr Skopintsev, Steffen Brünle, , Jörg Standfuss
The paper captures the release of a photopharmacological drug from tubulin using time-resolved serial crystallography and shows how ligand release triggers conformational changes.
Nature Communications · Feb 17, 2023Peer-reviewedMolecular Biology
A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia
Feng Long, Li Lin, Hongbiao Shi, Pengyu Li, Shaoqiang Guo, Yuer Ma, Yan Li, Shijun Wei, Fei Gao, Shang Gao, Meitian Wang, Ruonan Duan, Xiaojing Wang, Kun Yang, Liu Ai, , Qiji Liu
bioRxiv · Jan 27, 2020 · PreprintGenomics