Author

Tafadzwa Chigumira

Carnegie Mellon UniversityORCID 0000-0002-5366-8587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

David M. ChenowethiD· 2 shared Huaiying ZhangiD· 2 shared Rachel M. LackneriD· 2 shared Allison WivaggiD· 1 shared Deb Sankar BanerjeeiD· 1 shared Graham DellaireiD· 1 shared Jayme SalsmaniD· 1 shared Josiah C. KratziD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

David M. ChenowethORCID

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2 papers

Recent·Most cited

Telomeric SUMO level influences the choices of APB formation pathways and ALT efficiency

Rongwei Zhao, Xiaoyang Yu, Tafadzwa Chigumira, Meng Xu, Allison Wivagg, Rachel M. Lackner, Jayme Salsman, Graham Dellaire, Michael J. Matunis, David M. Chenoweth, Xiaolan Zhao, Huaiying Zhang

This study shows that high telomeric SUMO levels promote APB nucleation and enhance ALT efficiency through BLM recruitment and DNA synthesis.

The Journal of Cell Biology · Jun 10, 2025Peer-reviewedCell Biology

Interplay of condensate material properties and chromatin heterogeneity governs nuclear condensate ripening

Deb Sankar Banerjee, Tafadzwa Chigumira, Rachel M. Lackner, Josiah C. Kratz, David M. Chenoweth, Shiladitya Banerjee, Huaiying Zhang

The paper investigates how condensate material properties and chromatin heterogeneity influence nuclear condensate growth, revealing two physical mechanisms and a quantitative theory to explain these dynamics.

bioRxiv · May 7, 2024 · PreprintBiophysics