Hengrui Liu

This paper investigates the structural impact of glycosylation on the β3-subunit of voltage-gated sodium channels using glycan profiling and molecular dynamics simulations.

The paper provides pan-cancer profiles of 16 mitotic DNA integrity checkpoint protein kinase genes across multiple omic layers to identify potential biomarkers and therapeutic targets.

This study uses molecular modeling and simulations to show that N-linked glycans on Nav channel alpha-subunits may block beta-subunit Ig-domain binding and influence channel clustering.

This study finds RAD50 expression is lower in breast cancer and higher expression is linked to poorer survival, suggesting it as a potential biomarker for diagnosis and prognosis.

This study identifies MET and MERTK as frequently mutated protein kinases in cancer, with associations to survival and therapeutic response.

The paper analyzes pan-cancer profiles of 17 mitotic intra-S DNA damage checkpoint genes across 9000+ samples to identify potential diagnostic, prognostic, and therapeutic biomarkers.

This study analyzes mitochondrial DNA repair genes across cancers, finding TP53 mutations and CNV impacts on survival, and links these genes to cell cycle activation and drug response.

This paper analyzes pan-cancer genomics and clinical associations of disulfidptosis-related genes across multiple cancer types, identifying key mutations, survival correlations, and potential therapeutic targets.