Viral microRNA regulation of Akt is necessary for reactivation of Human Cytomegalovirus from latency in CD34+ hematopoietic progenitor cells and humanized mice
Nicole L. Diggins, Andrew H. Pham, Jennifer Mitchell, Christopher J. Parkins, Luke Slind, Rebekah Turner, Byeong-Jae Lee, Andrew D. Yurochko, Patrizia Caposio, Jay A. Nelson, Meaghan H. Hancock
This study shows that HCMV miRNAs downregulate Akt to promote reactivation from latency in CD34+ cells and humanized mice.
PLoS Pathogens · Dec 11, 2024Peer-reviewedMicrobiology