Author

Alison Fanton

University of California, San FranciscoORCID 0000-0002-5404-1460Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Juliana Q. Martins· 2 shared Liam J. BartieiD· 2 shared Matthew G. DurrantiD· 2 shared Patrick D. HsuiD· 2 shared Silvana KonermanniD· 2 shared Alexander MarsoniD· 1 shared April PawlukiD· 1 shared Chiara Ricci-TamiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioengineering

Juliana Q. Martins

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2 papers

Recent·Most cited

BioengineeringNature BiotechnologyPeer-reviewedNov 6, 2025

Site-specific DNA insertion into the human genome with engineered recombinases

Alison Fanton, Liam J. Bartie, Juliana Q. Martins…·Patrick D. Hsu

This study engineers recombinases to improve DNA insertion efficiency and specificity in human cells, achieving 53% integration and 97% genome-wide specificity.

29 citationstop 1%

humanexperimental assay

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BioengineeringSciencePeer-reviewedSep 25, 2025

Megabase-scale human genome rearrangement with programmable bridge recombinases

Nicholas Thomas Perry, Liam J. Bartie, Dhruva Katrekar…·Patrick D. Hsu

This paper describes the engineering of IS622 bridge recombinases to enable efficient and specific DNA rearrangements in the human genome, including insertion, inversion, and excision of up to 0.93 megabases.

41 citationstop 1%

humanwhole-genome sequencing

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