Ralf Mikut

Organotchi automates segmentation and morphological analysis of neural organoids, quantifying features and tracking changes over time to improve quality assessment and downstream analysis.

This study uses single-cell transplantation and mathematical modeling to show that lineage biases in hematopoiesis arise from extrinsic feedback and clonal competition, not intrinsic HSC properties.

Entomoscope 2.0 and ENIMAS 2.0 provide an open-source, AI-integrated platform for rapid, affordable insect digitization, achieving faster processing than commercial systems.

ObiWan-Microbi provides a cloud-based platform for semi-automated image annotation in microfluidic live-cell imaging using deep learning segmentation.

This paper introduces an AI-based pipeline for analyzing cerebral organoids using MRI, achieving high segmentation accuracy and quality classification.

microbeSEG provides a deep learning tool for automated cell segmentation in microbial cultures, achieving accurate results within 45 minutes of user time.

The paper shows that noise improves synchronization of a population of oscillators to external signals by increasing sensitivity and speeding up adjustment to phase changes.

This paper introduces a graph-based cell tracking algorithm with few parameters and automatic segmentation error correction, showing strong performance on degraded segmentation data.

The paper improves a competitive cell tracking algorithm by optimizing training parameters and data augmentation, achieving better performance in the Cell Tracking Challenge 2021.

The paper develops a stochastic oscillator model to simulate how light entrains zebrafish circadian clocks and applies it to predict effects of pharmacological treatments on entrainment dynamics.

This paper demonstrates that predicting movement in freely moving C. elegans enables high-quality MRI reconstruction by compensating for motion artifacts.

The paper shows that multipotent progenitors separate specialized stem zones in chick embryos through extrinsic morphogenetic cues rather than intrinsic fate determination.