Systems BiologyAging CellPeer-reviewed
Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging
Emin Onur Karakaslar, Neerja Katiyar, Muneer G. Hasham…·Duygu Ucar
The paper identifies the transcriptional activation of Jun and Fos genes in the AP-1 complex as a conserved aging signature in immune cells, contributing to inflammaging across mouse strains and humans.