Neerja Katiyar

This study shows Menin inhibition reduces metastatic colonization of Ewing sarcoma in vivo by disrupting MYC target gene expression and Menin:MYC interactions.

This study shows that BET inhibitor treatment rewires Ewing sarcoma transcription, increasing dependency on FAK, and that combining BET and FAK inhibitors synergistically reduces tumor growth.

The paper designs TrkA agonists that activate neuronal differentiation and neurite outgrowth without triggering pain-related gene expression.

This study creates a single-cell aging atlas of mouse mammary tissues, identifying shared epigenomic and transcriptomic changes between aging and cancer.

The paper identifies the transcriptional activation of Jun and Fos genes in the AP-1 complex as a conserved aging signature in immune cells, contributing to inflammaging across mouse strains and humans.