NeuroscienceScience SignalingPeer-reviewed
Biased M1 positive allosteric modulators reveal novel role of phospholipase D in M1-dependent rodent cortical plasticity
Sean P. Moran, Zixiu Xiang, Catherine A. Doyle…·Peter Jeffrey Conn
The paper shows that phospholipase D is essential for M1 PAM-induced long-term depression in rodent prefrontal cortex, and biased M1 PAMs that do not activate PLD have distinct effects on cortical plasticity.
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