Molecular BiologybioRxivPreprint
SIRT6 activator fucoidan extends healthspan and lifespan in aged wild-type mice
Seyed Ali Biashad, Eric C. Hillpot, Francesco Morandini…·Vera A. Gorbunova
This study shows that fucoidan, a seaweed-derived polysaccharide, extends healthspan and lifespan in aged mice by activating SIRT6, which reduces LINE1 retrotransposon activity and epigenetic aging.
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