James Gornet

This paper introduces CIFM, a generative virtual tissue model that simulates transcriptional dynamics under therapeutic conditions to design immunotherapy strategies for cancer and autoimmune diseases.

This paper demonstrates that predictive coding can construct spatial maps from sensory data, enabling agents to navigate using internal representations of environments.

The paper analyzes dendritic and axonal arbors of inhibitory neurons to identify transcriptomic correlates of neuroanatomy.

The paper quantifies whole-brain XCI at single-cell resolution and finds a 60:40 paternal-to-maternal inactivation ratio that reduces disease penetrance in Fragile-X models.