Author

Mike Filius

Leiden UniversityORCID 0000-0002-5434-8358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Andy C. H. LiuiD· 1 shared Femke J. BoxmaniD· 1 shared Gianluca TurcoiD· 1 shared Hugo Minnee· 1 shared Isa H. A. RijkiD· 1 shared Jingming LiuiD· 1 shared Monika T. GnatzyiD· 1 shared Ramon S.M. RoothiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Andy C. H. LiuORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJul 23, 2025

Generative Design of High-Affinity Peptides Using BindCraft

Mike Filius, Thanasis Patsos, Hugo Minnee…·Sebastian J. Pomplun

This study uses BindCraft to design high-affinity peptides for protein targets, achieving nanomolar affinities for some targets and improving potency through stapling.

4 citations

protein structuredeep learning

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