Author

Jingming Liu

Leiden UniversityORCID 0009-0003-1007-1937Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Femke J. BoxmaniD· 2 shared Monika T. GnatzyiD· 2 shared Sebastian J. PompluniD· 2 shared Andy C. H. LiuiD· 1 shared Chenlu ZhangiD· 1 shared Edith van der NoliD· 1 shared Gianluca TurcoiD· 1 shared Hugo Minnee· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

Femke J. BoxmanORCID

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2 papers

Recent·Most cited

PROXINAUT: An Automation Platform for Rapid Hit-to-Degrader Discovery

Sean M. McKenna, Monika T. Gnatzy, Edith van der Nol, Femke J. Boxman, Chenlu Zhang, Xiaokang Jin, Jingming Liu, Jeroen Kortekaas, Xiaoyu Zhang, Sebastian J. Pomplun

PROXINAUT automates hit-to-degrader discovery by integrating library screening with parallel synthesis, resulting in validated degraders with improved binding affinity.

bioRxiv · Sep 23, 2026 · PreprintBioengineering

Generative Design of High-Affinity Peptides Using BindCraft

Mike Filius, Thanasis Patsos, Hugo Minnee, Gianluca Turco, Jingming Liu, Monika T. Gnatzy, Ramon S.M. Rooth, Andy C. H. Liu, Rosa D. T. Ta, Isa H. A. Rijk, Safiya Ziani, Femke J. Boxman, Sebastian J. Pomplun

This study uses BindCraft to design high-affinity peptides for protein targets, achieving nanomolar affinities for some targets and improving potency through stapling.

bioRxiv · Jul 23, 2025 · PreprintBiochemistry