Author

Femke J. Boxman

Centre for Human Drug ResearchORCID 0009-0007-8713-5459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Jingming LiuiD· 2 shared Monika T. GnatzyiD· 2 shared Sebastian J. PompluniD· 2 shared Andy C. H. LiuiD· 1 shared Chenlu ZhangiD· 1 shared Edith van der NoliD· 1 shared Gianluca TurcoiD· 1 shared Hugo Minnee· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

Jingming LiuORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 23, 2026

PROXINAUT: An Automation Platform for Rapid Hit-to-Degrader Discovery

Sean M. McKenna, Monika T. Gnatzy, Edith van der Nol…·Sebastian J. Pomplun

PROXINAUT automates hit-to-degrader discovery by integrating library screening with parallel synthesis, resulting in validated degraders with improved binding affinity.

DOI 10.64898/2026.09.22.753586

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BiochemistrybioRxivPreprintJul 23, 2025

Generative Design of High-Affinity Peptides Using BindCraft

Mike Filius, Thanasis Patsos, Hugo Minnee…·Sebastian J. Pomplun

This study uses BindCraft to design high-affinity peptides for protein targets, achieving nanomolar affinities for some targets and improving potency through stapling.

4 citations

protein structuredeep learning

𝕏 PostBluesky