Rex A. Moats

Advancing Clinical Response Against Glioblastoma: Evaluating SHP1705 CRY2 Activator Efficacy in Preclinical Models and Safety in Phase I Trials

This paper evaluates the safety and efficacy of SHP1705, a CRY2 activator, in preclinical models and Phase I trials, showing improved efficacy against GBM stem cells and synergistic effects with a REV-ERB agonist.

Mouse Brain Extractor: Brain segmentation of mouse MRI using global positional encoding and SwinUNETR

The paper develops a deep learning method for mouse MRI brain segmentation using global positional encoding, achieving high accuracy and outperforming existing methods.

Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids

The paper describes the generation of a human cone photoreceptor reporter line using CRISPR/Cas9 and demonstrates its use for live imaging of cone maturation in retinal organoids.

On growth and form of the distal air exchange surfaces within the lung.

The paper uses novel imaging and computational approaches to deduce how distal air exchange surfaces in the lung form through epithelial buckling and extrusion, stabilized by elastin and collagen rings.

On Growth And Form Of The Distal Air Exchange Surfaces Within The Lung

The paper uses imaging and computational methods to propose a mechanism for the formation of the distal air exchange surfaces in the lung, involving epithelial buckling and stabilization by elastin and collagen.