Wei Shi

This study identifies defective mesenchymal Bmpr1a-mediated BMP signaling as a cause of congenital pulmonary cysts by disrupting lung branching morphogenesis and airway structure.

This study generates lung-specific mesenchyme from mouse iPSCs, identifies key signaling pathways, and demonstrates functional interactions with lung epithelial progenitors.

This study shows that Gremlin, an inhibitor of BMP, promotes AT2 cell proliferation and differentiation into AT1s during lung injury, facilitating alveolar repair.

The paper uses novel imaging and computational approaches to deduce how distal air exchange surfaces in the lung form through epithelial buckling and extrusion, stabilized by elastin and collagen rings.

The paper uses imaging and computational methods to propose a mechanism for the formation of the distal air exchange surfaces in the lung, involving epithelial buckling and stabilization by elastin and collagen.