Dwight F. Newton

The paper identifies 142 cryptic splices in ALS and FTD tissues, revealing divergent splicing between spinal cord and cortex, and highlights TDP43-independent events.

The paper identifies that somatostatin processing is a vulnerability factor in SST+ neurons under ER stress, linking chronic stress to behavioral deficits.

The paper investigates transcriptomic changes in cortical microcircuit cell types under chronic stress and finds coordinated shifts in gene expression patterns associated with altered excitation-inhibition balance.

The paper integrates transcriptomic data with in-silico analyses to identify cellular, molecular, and causal pathways in trait and state depression.

This study examines how chronic stress affects behavior and molecular markers in mice, showing gender-specific differences in molecular responses and behavioral outcomes.