Author

Rena Yang

California Institute of TechnologyORCID 0009-0009-6182-0276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Elizabeth Wei-Chia LuoiD· 2 shared Gerard C. L. WongiD· 2 shared Haleh AlimohamadiiD· 2 shared Shivam GuptaiD· 2 shared Taraknath MandaliD· 2 shared Anne BieveriD· 1 shared Brad A. FriedmaniD· 1 shared Dwight F. NewtoniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

Elizabeth Wei-Chia LuoORCID

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3 papers

Recent·Most cited

NeuroscienceMolecular Neurodegeneration AdvancesPeer-reviewedJan 6, 2026

Divergent TDP43-regulated and TDP43-independent cryptic splicing in the cortex and spinal cord

Dwight F. Newton, Rena Yang, Johnny Gutierrez…·Brad A. Friedman

The paper identifies 142 cryptic splices in ALS and FTD tissues, revealing divergent splicing between spinal cord and cortex, and highlights TDP43-independent events.

12 citationstop 1%

humanbulk RNA-seq

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BiophysicsJournal of the American Chemical SocietyPeer-reviewedJul 8, 2025

Dynamins combine mechano-constriction and membrane remodeling to enable two-step mitochondrial fission via a snap-through instability.

Haleh Alimohamadi, Elizabeth Wei-Chia Luo, Xiaoying Liu…·Gerard C. L. Wong

This study shows how dynamin proteins use mechano-constriction and membrane curvature to drive mitochondrial fission through a snap-through instability.

4 citations

mechanistic / dynamical modelcell signaling & trafficking

𝕏 PostBluesky

BiophysicsACS NanoPeer-reviewedJun 5, 2024

Comparing multifunctional viral and eukaryotic proteins for generating scission necks in membranes

Haleh Alimohamadi, Elizabeth Wei-Chia Luo, Shivam Gupta…·Gerard C. L. Wong

This study compares the membrane scission capabilities of viral and eukaryotic proteins using mechanical models and SAXS data to analyze how lipid composition and interfacial tension affect neck size.

7 citations

virusyeast

𝕏 PostBluesky