Osama Abdin

ZATELLITE: a toolkit to visualize and manipulate human centromeres in live cells using synthetic zinc fingers

ZATELLITE enables real-time visualization and manipulation of human centromeres in live cells using synthetic zinc fingers without causing DNA damage.

Scalable emulation of protein equilibrium ensembles with generative deep learning

BioEmu, a diffusion model trained on structures, molecular dynamics trajectories, and stability assays, samples protein equilibrium ensembles and folding free energies within ~1 kcal/mol in GPU-hours.

PepFlow: direct conformational sampling from peptide energy landscapes through hypernetwork-conditioned diffusion

PepFlow samples peptide conformations using a diffusion-based Boltzmann generator with hypernetworks, achieving faster and accurate predictions than traditional methods.

PepNN: a deep attention model for the identification of peptide binding sites

PepNN introduces deep attention models for predicting peptide binding sites on proteins using sequence and structural data, achieving high performance on benchmark tests.