Author

Néstor Saiz

Memorial Sloan Kettering Cancer CenterORCID 0000-0003-0637-791XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:fluorescence / live-cell microscopy· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:deconvolution· 1 Approach:deep learning· 1

Frequent Co-Authors

Anna‐Katerina HadjantonakisiD· 2 shared Finnegan ClarkiD· 2 shared Peter H. WhitneyiD· 2 shared Timothée LionnetiD· 2 shared Aleah GoldbergiD· 1 shared Angelina ZiarnoiD· 1 shared Claire S. SimoniD· 1 shared Dana Pe’eriD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Anna‐Katerina HadjantonakisORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 5, 2026

ZATELLITE: a toolkit to visualize and manipulate human centromeres in live cells using synthetic zinc fingers

Néstor Saiz, Aleah Goldberg, Finnegan Clark…·Timothée Lionnet

ZATELLITE enables real-time visualization and manipulation of human centromeres in live cells using synthetic zinc fingers without causing DNA damage.

DOI 10.64898/2026.08.04.742839

humanfluorescence / live-cell microscopy

𝕏 PostBluesky

BiophysicsbioRxivPreprintNov 25, 2025

BeadBuddy: user-friendly, nanometer-scale registration of single-molecule imaging data

Finnegan Clark, Peter H. Whitney, Néstor Saiz…·Timothée Lionnet

BeadBuddy corrects chromatic errors in single-molecule imaging data using fluorescent bead images, achieving sub-voxel resolution in DNA FISH and applicable across SMLM modalities.

DOI 10.1101/2025.11.25.690467

fluorescence / live-cell microscopydeep learning

𝕏 PostBluesky

Developmental BiologyeLifePeer-reviewedJul 27, 2020

Growth factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development

Néstor Saiz, Laura Mora-Bitria, Shahadat Rahman…·Anna‐Katerina Hadjantonakis

The paper develops a mathematical model showing growth factor signaling ensures robustness in mammalian embryo development by coupling lineage size and cell fate choice.

92 citationstop 3%

mousestatistical model

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Developmental BiologybioRxivPreprintNov 15, 2018

Charting the emergent organotypic landscape of the mammalian gut endoderm at single-cell resolution

Sonja Nowotschin, Manu N. Setty, Ying-Yi Kuo…·Dana Pe’er

The paper maps the developmental trajectories of endoderm cells in the mouse embryo to reveal lineage relationships and spatial organization during gut formation.

7 citations

mousescRNA-seq

𝕏 PostBluesky