BiophysicsNature CommunicationsPeer-reviewed
Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor
Ashok Ranjan Nayak, Warin Rangubpit, Alex H. Will…·Montserrat Samsó
The paper determines cryo-EM structures of RyR1 with Mg2+ and identifies multiple Mg2+ binding sites, revealing its inhibitory mechanism and interaction with gating helices.
25 citations