Author

Joshua J. Lobo

Virginia Commonwealth UniversityORCID 0000-0002-6236-7671Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Alex H. WilliD· 1 shared Ashok Ranjan NayakiD· 1 shared Graham D. LambiD· 1 shared Kelly A. DrydeniD· 1 shared Montserrat SamsóiD· 1 shared Pablo Castro‐HartmanniD· 1 shared Pornthep SompornpisutiD· 1 shared Warin RangubpitiD· 1 shared

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2024-2024 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Alex H. WillORCID

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1 paper

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedMay 15, 2024

Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor

Ashok Ranjan Nayak, Warin Rangubpit, Alex H. Will…·Montserrat Samsó

The paper determines cryo-EM structures of RyR1 with Mg2+ and identifies multiple Mg2+ binding sites, revealing its inhibitory mechanism and interaction with gating helices.

25 citations

cryo-EMexperimental assay

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