BiochemistryACS Chemical BiologyPeer-reviewed
Select azo compounds post-translationally modulate HTRA1 abundance and activity potentially through interactions at the trimer interface
John D. Hulleman, Seungje Jeon, Sofia Bali…·Bruce A. Posner
This paper identifies specific azo compounds that enhance HTRA1 abundance but have varying effects on its activity, suggesting potential therapeutic applications for diseases like AMD.
DOI 10.1021/acschembio.4c00818