Cell BiologyCommunications BiologyPeer-reviewed
Reverse transcriptase inhibitors induce autophagy in a LINE-1 ORF1p-dependent manner
Michela Damizia, Mirko Baranzini, Ilaria Sciamanna…·Corrado Spadafora
This study shows reverse transcriptase inhibitors induce autophagy in cancer cells through LINE-1 ORF1p-dependent mechanisms involving DNA damage and lamin B1 interactions.
DOI 10.1038/s42003-026-10900-x