Anton Steen

Conserved intrinsically disordered region of DNAJB6 dictates its surveillance of FG-Nup condensates

The paper shows that DNAJB6's conserved intrinsically disordered region enables its surveillance of FG-Nup condensates by forming stable assemblies that outcompete FG-Nup interactions.

Detecting Nuclear Pore Complex assembly in living cells

This paper introduces a nanobody-based method to detect newly forming nuclear pore complexes in yeast, revealing novel insights into their assembly and localization.

Imaging-Based Quantitative Assessment of Biomolecular Condensates in vitro and in Cells

The paper introduces PhaseMetrics, an image analysis pipeline for quantifying biomolecular condensates in vitro and in cells, showing its accuracy across different experimental systems.

Specificity and mechanism of 1,6 hexanediol-induced disruption of nuclear transport

This study investigates how 1,6-hexanediol disrupts nuclear pore complex permeability in yeast by displacing nuclear transport receptors without affecting NPC subunits or cell viability.

The molecular chaperone DNAJB6 provides surveillance of FG-Nups and is required for interphase nuclear pore complex biogenesis

This study identifies DNAJB6 as a molecular chaperone that prevents FG-Nup aggregation during interphase nuclear pore complex biogenesis.