Jonas S. Fischer

A tool to pulse-label yeast Nuclear Pore Complexes in imaging and biochemical experiments

The paper introduces a method to pulse-label yeast Nuclear Pore Complexes using a nanobody, enabling tracking in imaging and biochemical experiments.

The chaperone Jjj2 regulates nucleoporin condensation in budding yeast

This study identifies Jjj2 as a chaperone that regulates nucleoporin condensation in budding yeast, showing its role in maintaining NPC permeability and preventing aggregation.

A conserved mechanism of membrane fusion in nuclear pore complex assembly

This study identifies Brl1 and Brr6 as conserved fusogens mediating membrane fusion during NPC assembly in eukaryotes.

The environmental stress response controls the biophysical properties of the cytoplasm and is critical for survival in quiescence

This study shows that respiration-induced gene expression and stress response pathways are critical for maintaining cytoplasmic properties and survival in yeast quiescence.

Detecting Nuclear Pore Complex assembly in living cells

This paper introduces a nanobody-based method to detect newly forming nuclear pore complexes in yeast, revealing novel insights into their assembly and localization.