BiophysicsbioRxivPreprint
A Structural Domain in the genomic RNA of SARS-CoV-2 Folds into a Compact Granular Structure without the N protein: A Single-Molecule Fluorescence Spectroscopic Investigation
Takahiro Kimura, Takuya Katayama, Shion Ishikawa…·Satoshi Takahashi
This study shows a specific SARS-CoV-2 genomic RNA region forms compact granular structures autonomously without the N protein, and the N protein melts these structures, suggesting it acts as an RNA chaperone.
DOI 10.64898/2026.05.15.725307