Daiki Setoyama

Multi-Omics Mapping of Human Kidney Reveals Complement-Mediated Cellular Dynamics During Progression of Focal Segmental Glomerulosclerosis

This study uses multi-omics approaches to analyze human kidney biopsies and identifies complement-mediated cellular dynamics in FSGS progression, highlighting key signaling changes in podocytes and parietal epithelial cells.

Leveraging Machine Learning to Uncover the Hidden Links between Trusting Behavior and Biological Markers

This study uses a Bayesian hierarchical model to decode decision-making properties from trust game data, identifying biomarkers linked to trusting behavior in MDD patients and healthy controls.

A nucleic acid prodrug that activates mitochondrial respiration, promotes stress resilience, and prolongs lifespan

This study develops a nucleic acid prodrug that boosts mitochondrial respiration, increases ATP levels, and extends lifespan in C. elegans by enhancing energy metabolism and stress resilience.

MitoNEET reduces the mitochondrial oxidative phosphorylation during epithelial-mesenchymal transition

This study shows that mitoNEET downregulation during EMT impairs OXPHOS and cell motility in mouse mammary epithelial cells.

Characterization and function of medium and large extracellular vesicles from plasma and urine by surface antigens and Annexin V

The paper characterizes medium/large extracellular vesicles (m/lEVs) from plasma and urine using surface antigens and Annexin V, identifying their sources and functional differences.